Sigma Aldrich / Merck - B102-50MG - Bupropion hydrochloride

ITEM #: 9150848
Synonym: (±) - 1- (3- Chlorophenyl) - 2- [(1, 1- dimethylethyl) amino] - 1- propanone hydrochloride Bupropion is structurally linked to the phenylethylamine family. It is a monocyclic aminoketone (chloropropiophenone).
Bupropion hydrochloride has been used as an anti-depressant and injected into mice intraperitoneally for forced swim test. It has also been used to study its effects on depression, anxiety and smoking cessation.
1 g in poly bottle
50, 250 mg in poly bottle
Bupropion possesses antidepressant and anxiolytic properties. It serves as a good auxiliary for people who makes an effort to give up smoking. It may also be used in the treatment for attention-deficit hyperactivity disorder.
Inhibits the dopamine and norepinephrine transporters with K i s of 2.8 μM and 1.4 μM, respectively. Does not inhibit the serotonin transporter (K i = 45 μM). Antidepressant.
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