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Sigma Aldrich / Merck - D3900-25G - Desipramine hydrochloride

  • MFR SKU: D3900-25G
  • ITEM #: 16104316
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ITEM #: 16104316
Desipramine, a metabolite of imipramine and iofepramine is an active tricyclic antidepressant.
Desipramine hydrochloride has been used: • to prevent norepinephrine neuron degeneration and to maximize uptake into DA neurons • to protect unselective damage to the noradrenergic system • as a norepinephrine re-uptake inhibitor to treat rats for lesioning
1, 5, 25 g in glass bottle
Desipramine is used to treat depression. It is also used to manage enuresis in children....
ITEM #: 16104316
Desipramine, a metabolite of imipramine and iofepramine is an active tricyclic antidepressant.
Desipramine hydrochloride has been used: • to prevent norepinephrine neuron degeneration and to maximize uptake into DA neurons • to protect unselective damage to the noradrenergic system • as a norepinephrine re-uptake inhibitor to treat rats for lesioning
1, 5, 25 g in glass bottle
Desipramine is used to treat depression. It is also used to manage enuresis in children. Desipramine helps to eliminate the pain triggered by diabetic neuropathy.
Tricyclic antidepressant that is a more potent inhibitor of the norepinephrine transporter (K i = 4 nM) than the serotonin transporter (K i = 61 nM).
This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC 1280 ), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.
This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
This compound was developed by Sanofi Aventis . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Hygroscopic
LOPAC is a registered trademark of Sigma-Aldrich Co. LLC
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Sigma Aldrich / Merck - D3900-25G - Desipramine hydrochloride

  • Item #: 16104316
  • MFR SKU: D3900-25G
Technical Specs
  • Quality Level :100
  • assay :≥ 98% (TLC)
  • form :powder
  • color :white to off-white
  • solubility :H 2 O: 50 mg/mL
  • originator :Sanofi Aventis
  • storage temp. :2-8° C
  • SMILES string :Cl[H].CNCCCN1c2ccccc2CCc3 ccccc13
  • InChI :1S/ /c1-19-13- 6-14-20-17-9-4-2-7-15(17) 11-12-16-8-3-5-10-18(16)2 0;/h2-5, 7-10, 19H, 6, 11-14H 2, 1H3; 1H
  • InChI key :XAEWZDYWZHIUCT-UHFFFAOYSA -N
  • Gene Information :human ... SLC6A2 (6530)
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